The Neuroscience Laboratory (LabNeuro) was created in 2006 and is headed by Dr. Daniela Martí Barros and Dr. Ana Paula Horn, both from the Post-graduate Program in Physiological Sciences.
This laboratory is engaged in several research projects. Neuropsycopharmacology: the objective of this group is to investigate the action of substances in the central nervous system. It evaluates memory parameters in various animal models, such as rodents and zebrafish, using numerous behavioral tasks, including contextual fear conditioning, inhibitory avoidance, water maze, open field, elevated plus maze and object recognition. Additionally, the group correlates biochemical, molecular and signal transduction results with the behavioral performance of animals on the above-mentioned tasks. Nanomaterials toxicology: the objective of this group is to investigate the effects of various nanomaterials on the central nervous system, correlating histological, cellular and molecular findings with the possible toxicity of the compounds. Neuroprotective strategies for intracerebral hemorrhage: the objective of this group is to investigate the intracerebral hemorrhage-induced mechanism of cellular death. Additionally, it investigates the possible neuroprotective effect on this condition of stem cells and various compounds isolated from plants. Antitumoral compounds against glioblastoma multiforme: the objective of this group is to investigate compounds that may have antitumoral properties against glioblastoma multiforme. The group tests cultures of multiple glioma cell lines to investigate the mechanisms of promising molecules.
In addition, LabNeuro, in collaboration with the Research Group in Neuroscience and Education (GPNED), are involved in scientific dissemination. For example, the laboratory participates in NEUROEDUCA: Neuroscience for everyone, an annual event whose main objective is to expose everyone to the basic concepts of neuroscience and to teach them how to apply these concepts in their daily activities.